- 2/24/12: Lions take down No.2 North Georgia and No.25 Flagler College in back-to-back games. (Highest ranked opponent defeated since a 3-1 defeat of No.1 Alabama Huntsville on March 3, 2008)
- 2/10/12: Brittany Yates blasts 33rd career home run (grand slam) in come-from-behind win over Barry. The home run tied the all-time home run record at Saint Leo (Ashley Urbanik).
- 3/21/12: Brittany Yates blasts 34th career home run in 9-8 win over Fontbonne to become program leader in career home runs. (3-1 pitch; Sismilich scored; Rachel McCarthy - pitcher).
- 3/24/12: Megan Still collects season-high eight strikeouts in 2-1 loss to Palm Beach Atlantic.
